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The mice are then treated topically with in a microemulsion, for example, a microemulsion as described above in the microemulsion formulation examples 1 to 5 wherein the active agents include one or more of the following chemotherapeutic agents: 5 -fluorouracil (10 mgml, 20 microlitre dose, 2 times per day); Carboplatin (10 mgml, 20 microlitre dose, 2 times per day); Cis-Platinum (10 mgml, 20 microlitre dose, 2 times per day); or a control microemulsion without chemotherapeutic agents. After 4 days of treatment, there is anticipated to be a reduction in growth rate of the tumour but no reduction in body weight of the animals.]