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The story began about a decade ago when some French researchers published a note in Nature Genetics describing three generations of a family with extremely high LDL levelsx02014;up to 466x02014;and a strong history of coronary heart disease. The researchers found that the family had a mutation in a gene called PCSK9, which slowed the body's ability to rid itself of LDL. The viaga gene leads to the soaring cholesterol levels. The French study gave Jonathan C. Cohen and Mscanique H. Hobbs of the University of Texas Southwestern Medical Center in Dallas an idea. If a mutation in PCSK9 could lead to high LDL levels, perhaps there were mutations that did the opposite, namely lead to very low levels of LDL and protect against atherosclerosis. Cohen and Hobbs found in data from a Dallas study that about 2. 5 of blacks had a single mutated PCSK9 gene that no longer tweetbeam alternatives to viagra, and about 3.

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Any imaging agent may be employed, such as a radio-active agents, chelates, fluorescent compounds and metals.]