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The average cost to global pharmaceutical companies of opening a single General Practitioner site is between 25,000 and 37,000, yet 40 of these sites will recruit only one patient, Synexus pointed out. According to CenterWatch Trials Listings 2006, the industry average for the number of patients recruited per site is below five. All the same, Synexus noted, the market for clinical trials continues to grow, driven by ‚industry‚s need to innovate, combined with more stringent safety regulations in the post-Vioxx era‚. Spending on contract research grants is expected to rise at a compound annual growth rate of 14.

Most, if not all of these businesses, have risen without trace. It would seem that they did not understand the needs of business quite as well as they had predicted.]